Beyond symptom relief, a breakthrough device designed to treat the underlying cause of COPD with Chronic Bronchitis
Beyond symptom relief, a breakthrough device designed to treat the underlying cause of COPD with Chronic Bronchitis
Introduction to RejuvenAir®
The RejuvenAir System is a revolutionary cryosurgical device which applies a precise thermal dose or “metered cryospray” of extremely cold, -196°C liquid nitrogen to targeted areas within the lungs through a minimally invasive, often outpatient or same-day bronchoscopic procedure.
CAUTION: Investigational device. Limited by Federal law to investigational use.
About COPD with Chronic Bronchitis
Chronic Bronchitis is the largest disease subset of Chronic Obstructive Pulmonary Disease (COPD).
Unlike common Bronchitis, which is acute and clears up quickly, Chronic Bronchitis (CB) is characterized by a long-term productive cough, breathlessness and/or wheezing as well as a tight chest sensation.
The persistent cough itself can be debilitating. Patients with Chronic Bronchitis often avoid social situations and give up activities, further contributing to a decline in overall well-being and quality of life. While current medications help alleviate symptoms, they don’t address the underlying cause of the disease and are largely ineffective.
How Metered Cryospray Works
The RejuvenAir System delivers small, metered doses of cryogen spray which flash freeze the surface area of damaged airways. Diseased cells are destroyed, leaving behind the extra-cellular structure that allows for new healthy cells, including cilia and mucus-producing goblet cells, to repopulate.
RejuvenAir rejuvenates the airways.
How Metered Cryospray Works
-196° C flash freeze causes instant cell death
Preservation of extracellular matrix (ECM)
Intact ECM enables healing with limited scarring and fibrosis
The RejuvenAir System delivers small, metered doses of cryogen spray which flash freeze the surface area of damaged airways. Diseased cells are destroyed, leaving behind the extra-cellular structure that allows for new healthy cells, including cilia and mucus-producing goblet cells, to repopulate.
RejuvenAir rejuvenates the airways.
The SPRAY-CB Clinical Trial
Researching a NEW option for people living with Chronic Bronchitis
The RejuvenAir System Trial for COPD with Chronic Bronchitis (SPRAY-CB) aims to evaluate the effectiveness of the RejuvenAir System to reduce mucous production, cough, and inflammation in the Chronic Bronchitis patient population and to determine the extent of improvement in their overall health and quality of life.
Watch the video
| Title | Address | Description |
|---|---|---|
Temple University, Philadelphia | 1801 N Broad St, Philadelphia, PA 19122, USA | Principal Investigator: Dr. G.J. Criner, Interventional Pulmonology /Pulmonary Care. |
UC Davis Medical Center, Sacramento | 2279 45th St, Sacramento, CA 95817, USA | Principal Investigator: Dr. Ken Yoneda, Interventional Pulmonology /Pulmonary Care |
UT Southwestern Medical Center, Dallas | 5939 Harry Hines Blvd, Dallas, TX 75390, USA | Principal Investigator: Dr. Muhanned Abu-Hijleh, Interventional Pulmonology /Pulmonary Care |
El Camino Hospital, Mountain View | 701 E El Camino Real, Mountain View, CA 94040, USA | Principal Investigator: Dr. Ganesh Krishna, Interventional Pulmonology /Pulmonary Care |
Beth Israel Deaconess Medical Center, Boston | 185 Pilgrim Rd, Boston, MA 02215, USA | Principal Investigator: Dr. Adnan Majid, Interventional Pulmonology /Pulmonary Care |
Sarasota Memorial Hospital, Sarasota | 1700 S Tamiami Trail, Sarasota, FL 34239, USA | Principal Investigator: Dr. Joseph Seaman, Interventional Pulmonology /Pulmonary Care |
Medical University of South Carolina, Charleston | 96 Jonathan Lucas St, Charleston, SC 29425, USA | Principal Investigator: Dr. Charlie Strange, Interventional Pulmonology /Pulmonary Care |
Duke University School of Medicine, Durham | Durham, NC, USA | Principal Investigator: Dr. Wahidi, Interventional Pulmonology /Pulmonary Care |
Advanced Pulmonary Research Institute, Loxahatchee | 13005 Southern Blvd, Loxahatchee, FL 33470, USA | Principal Investigator: Dr. Warshoff, Interventional Pulmonology /Pulmonary Care |
Cooper Health | New Brunswick, NJ, USA | Principal Investigator: Dr. Wissam Abouzgheib, Bronchoscopy & Interventional Pulmonology |
The Cleveland Clinic Foundation, Cleveland | 9500 Euclid Ave, Cleveland, OH 44106, USA | Principal Investigator: Dr. Gildea, Interventional Pulmonology /Pulmonary Care. |
University Of Wisconsin Hospital, Madison | Highland Ave, Madison, WI, USA | Principal Investigator: Dr. Ferguson, Interventional Pulmonology /Pulmonary Care |
Louisiana State University Medical Center, Shreveport | Shreveport, LA 71103, USA | Principal Investigator: Dr. Robert Holladay, Bronchoscopy & Interventional Pulmonology |
University of Cincinnati, Cincinnati | Lindner Hall, 2925 Campus Green Dr, Cincinnati, OH 45221, USA | Principal Investigator: Dr. Alejandro Adolfo Aragaki, Bronchoscopy & Interventional Pulmonology |
St. David's Medical Center, Austin | 1015 E 32nd St, Austin, TX 78705, USA | Principal Investigator: Dr. D. Dekeratry, Interventional Pulmonology |
University of Maryland, Baltimore | Um Professional Bldg, 419 W Redwood St, Baltimore, MD 21201, USA | Principal Investigator: Dr. Ashutosh Sachdeva, Interventional Pulmonology /Pulmonary Care. |
Clinical Research Associates of Central PA | 100 Hospital Ave, DuBois, PA 15801, USA | Principal Investigator: Dr. Sandeep Bansal, Bronchoscopy & Interventional Pulmonology |
Dartmouth-Hitchcock Medical Center, Lebanon | 1 Medical Center Dr, Lebanon, NH 03766, USA | ENROLLING |
Prisma Health-Midlands, Columbia | Columbia, SC, USA | Principal Investigator: Dr. W Tillis, Interventional Pulmonology /Pulmonary Care. |
Ohio State University, Columbus | Davis Heart and Lung Research Institute, 473 W 12th Ave, Columbus, OH 43210, USA | Principal Investigator: Dr. Christian Ghattas, Interventional Pulmonology /Pulmonary Care |
Spectrum Health, Grand Rapids | 4100 Lake Dr SE, Grand Rapids, MI 49546, USA | Principal Investigator: Dr. Cumbo-Nacelli, Interventional Pulmonology /Pulmonary Care |
HonorHealth, Scottsdale | Scottsdale, AZ, USA | Principal Investigator: Dr. Richard Sue, Interventional Pulmonology /Pulmonary Care |
ACTIVE, NOT RECRUITING
About Us
CSA Medical is committed to developing spray cryotherapy devices that improve the lives of people suffering from COPD with Chronic Bronchitis. We are advancing our core liquid nitrogen spray technology to target the underlying cause of Chronic Bronchitis – the over production of mucus and damaged cilia within the airways. By targeting and destroying these damaged cells without creating scar tissue, the body can begin the rapid regrowth of new, healthy normal functioning cells in the lung.
News & Resources
Data Presented at the American College of Chest Physicians Correlates Airway Remodeling with Positive Clinical Outcomes Utilizing the RejuvenAir® System
Underlying proof of rejuvenative healing indicative of airway remodeling corresponds with clinical efficacy and improved quality of life Boston, MA—Oct 8, 2024: /PRNewswire/ -- CSA Medical, Inc., a leader in developing spray cryotherapy solutions for the treatment of...
CSA Medical Announces New Scientific Data Utilizing Metered Cryospray with the RejuvenAir® System for the Treatment of Chronic Bronchitis
Research reveals rejuvenative changes in cellular populations indicative of airway remodeling correspond with clinical efficacy and improved quality of life BOSTON, Sept. 16, 2024 /PRNewswire/ --CSA Medical, Inc., today announced multiple presentations at the European...
CSA Medical Raises $53 Million in Series D Financing to Support PMA of the RejuvenAir System
TVM Capital Life Science and Yonjin Venture co-led the round, joined by a strong syndicate of existing investors BOSTON, Sept. 9, 2024 /PRNewswire/ -- CSA Medical Inc., developer of The RejuvenAir® System, a Breakthrough Medical Device advancing the power of liquid...
131 Hartwell Avenue
Lexington
Massachusetts 02421
CAUTION: Investigational device. Limited by Federal law to investigational use.